Micro- and Nanoparticle Translocation through a Solid-State Membrane Pore Thinner than their Diameters
نویسندگان
چکیده
منابع مشابه
Single Nanoparticle Translocation Through Chemically Modified Solid Nanopore
The nanopore sensor as a high-throughput and low-cost technology can detect single nanoparticle in solution. In the present study, the silicon nitride nanopores were fabricated by focused Ga ion beam (FIB), and the surface was functionalized with 3-aminopropyltriethoxysilane to change its surface charge density. The positively charged nanopore surface attracted negatively charged nanoparticles ...
متن کاملFast DNA translocation through a solid-state nanopore.
We report experiments and modeling of translocation of double-strand DNA through a siliconoxide nanopore. Long DNA molecules with different lengths ranging from 6500 to 97000 base pairs have been electrophoretically driven through a 10 nm pore. We observe a power-law caling of the translocation time with the length, with an exponent of 1.27. This nonlinear scaling is strikingly different from t...
متن کاملControlled Reverse Translocation of DNA Through a Solid - State
Submitted for the MAR10 Meeting of The American Physical Society Controlled Reverse Translocation of DNA Through a Solid-State Nanopore1 PAUL WEINGER, VENKAT BALAGURUSAMY, SUNGCHEOL KIM, XINSHENG SEAN LING, Brown University — Reverse DNA translocation [1] is a process in which a DNA is pulled out of a nanopore against the forward electric force. In this process, the effective diffusion constant...
متن کاملVelocity of DNA during translocation through a solid-state nanopore.
While understanding translocation of DNA through a solid-state nanopore is vital for exploiting its potential for sensing and sequencing at the single-molecule level, surprisingly little is known about the dynamics of the propagation of DNA through the nanopore. Here we use linear double-stranded DNA molecules, assembled by the DNA origami technique, with markers at known positions in order to ...
متن کاملDifferentiating Metastatic and Non-metastatic Tumor Cells from Their Translocation Profile through Solid-State Micropores.
Cancer treatment, care, and outcomes are much more effective if started at early stages of the disease. The presence of malignant cancer cells in human samples such as blood or biopsied tissue can be used to reduce overtreatment and underdiagnosis as well as for prognosis monitoring. Reliable quantification of metastatic tumor cells (MTCs) and non-metastatic tumor cells (NMTCs) from human sampl...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2011
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2010.12.3497